Possible interactions between garlic and conventional drugs: a review

Mital B. Kansara, Ashutosh J. Jani

Abstract


Herbs can affect body function; therefore, when herbs are taken concurrently with drugs, interactions are possible. The interaction between drugs and herbal medicines is a safe concern and these interactions are especially important for drugs with narrow therapeutics index. The probability of herb-drug interaction can be higher than drug interaction, if conventional drug having single chemical entities, whereas most of the herbal medicinal product contain a mixture of pharmacologically active constituents. The herb-drug interaction may involve either an increase or decrease in the amount of drug in blood, either by altering the absorption, distribution, metabolism, and elimination (ADME) of drug and by antagonizing or synergism of the effect of drug or pharmacodynamics interaction may arise. This article we focus on how garlic interacts with conventional drug or it is favourable or not.


Keywords


Herbal-drug interaction, Pharmacokinetic, Pharmacodynamics, Garlic, Interaction with the conventional drug

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DOI: http://dx.doi.org/10.26510/2394-0859.pbe.2017.12

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