<ArticleSet>
<Article>
<Journal>
<PublisherName>Onlinepbe</PublisherName>
<JournalTitle>Pharmaceutical and Biological Evaluations</JournalTitle>
<Issn>2394-0859</Issn>
<Volume>2</Volume>
<Issue>3</Issue>
<PubDate>
<Year>2015</Year>
<Month>07</Month>
<Day>22</Day>
</PubDate>
</Journal>
<ArticleTitle>Antimicrobial activities of volatile oil compound from the rhizome of Zingiber officinale using solvent method extraction</ArticleTitle>
<FirstPage>47</FirstPage>
<LastPage>51</LastPage>
<Language>EN</Language>
<AuthorList>
<Author>
<FirstName>Ugoh</FirstName>
<LastName>Sylvanus</LastName>
<Affiliation>Department of Biological Sciences, University of Abuja. subrat.sahu2008@gmail.com</Affiliation>
</Author>
<Author>
<FirstName>Fatokun</FirstName>
<LastName>Olakunle</LastName>
</Author>
<Author>
<FirstName>Olajide</FirstName>
<LastName>Olutayo</LastName>
</Author>
<Author>
<FirstName>Kabiru</FirstName>
<LastName>Usman</LastName>
</Author>
</AuthorList>
<Abstract>Objective: To characterize the chemical constituents and evaluate the antimicrobial activity of Zingiber officinale oil extracted with hexane.Methods: The air dried powdered rhizome of Z. officinale was extracted with n- hexane. The antimicrobial activity of Z. officinale oil extract was tested on gram positive and gram negative bacteria.Result: The extracted oil on GC-MS analysis resulted in the identification of 19 compounds, among which 13-Docosenoic acid was found to be the most abundant at 15.48 %. The preliminary antimicrobial screening of the oil from Z. officinale against four pathogens; Pseudomonas aeruginosa, Escherichia coli, Salmonella typhi and Staphylococcus aureus revealed that the mean zone diameter of inhibition (Z.O.I) is concentration dependent in which pseudomonas aeruginosa showed highest concentration at 100 %. The minimum inhibitory concentrations (MIC) values of the oil revealed these concentrations 12.5 %, 25 % 50 % and 100 % against the tested organisms respectively. The minimum bactericidal concentration (MBC) of the oil on S. aureus was recorded at 100% concentration, while E. coli, P. aeruginosa, and S. typhi were all resistant.Conclusion: This study showed that the oil from Z. officinale may be used to manage some infectious diseases caused by the tested organisms.</Abstract>
<Keywords>Zingiber officinale, Chemical constituents, Antimicrobial activities, Medicinal uses</Keywords>
<URLs>

Abstract

<Fulltext>
<pdf>http://onlinepbe.com/index.php/PBE/article/view/7/pdf5</pdf>
</Fulltext>
</URLs>
</Article>
</ArticleSet>

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